Inhibition of autophagy inhibits the conversion of cardiac fibroblasts to cardiac myofibroblasts

The incidence of heart failure with concomitant cardiac fibrosis is very high in developed countries. Fibroblast activation in heart is causal to cardiac fibrosis as they convert to hypersynthetic cardiac myofibroblasts. There is no known treatment for cardiac fibrosis. Myofibroblasts contribute to...

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Detalles Bibliográficos
Autores principales: Gupta, Shivika S., Zeglinski, Matthew R., Rattan, Sunil G., Landry, Natalie M., Ghavami, Saeid, Wigle, Jeffrey T., Klonisch, Thomas, Halayko, Andrew J., Dixon, Ian M.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346657/
https://www.ncbi.nlm.nih.gov/pubmed/27705938
http://dx.doi.org/10.18632/oncotarget.12392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346657/
https://www.ncbi.nlm.nih.gov/pubmed/27705938
http://dx.doi.org/10.18632/oncotarget.12392

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