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Fatty acid synthase is a primary target of MiR-15a and MiR-16-1 in breast cancer

Fatty acid synthase (FASN) is upregulated in breast cancer and correlates with poor prognosis. FASN contributes to mammary oncogenesis and serves as a bona fide target in cancer therapies. MicroRNAs inhibit gene expression through blocking mRNA translation or promoting mRNA degradation by targeting...

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Detalles Bibliográficos
Autores principales: Wang, Jingxuan, Zhang, Xiao, Shi, Jinming, Cao, Paul, Wan, Meimei, Zhang, Qiang, Wang, Yunxuan, Kridel, Steven J., Liu, Wennuan, Xu, Jianfeng, Zhang, Qingyuan, Sui, Guangchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346660/
https://www.ncbi.nlm.nih.gov/pubmed/27713175
http://dx.doi.org/10.18632/oncotarget.12479