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CCR10/CCL27 crosstalk contributes to failure of proteasome-inhibitors in multiple myeloma

The bone marrow microenvironment plays a decisive role in multiple myeloma progression and drug resistance. Chemokines are soluble mediators of cell migration, proliferation and survival and essentially modulate tumor progression and drug resistance. Here we investigated bone marrow-derived chemokin...

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Detalles Bibliográficos
Autores principales: Thangavadivel, Shanmugapriya, Zelle-Rieser, Claudia, Olivier, Angelika, Postert, Benno, Untergasser, Gerold, Kern, Johann, Brunner, Andrea, Gunsilius, Eberhard, Biedermann, Rainer, Hajek, Roman, Pour, Ludek, Willenbacher, Wolfgang, Greil, Richard, Jöhrer, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346663/
https://www.ncbi.nlm.nih.gov/pubmed/27732933
http://dx.doi.org/10.18632/oncotarget.12522