Cargando…
CCR10/CCL27 crosstalk contributes to failure of proteasome-inhibitors in multiple myeloma
The bone marrow microenvironment plays a decisive role in multiple myeloma progression and drug resistance. Chemokines are soluble mediators of cell migration, proliferation and survival and essentially modulate tumor progression and drug resistance. Here we investigated bone marrow-derived chemokin...
Autores principales: | Thangavadivel, Shanmugapriya, Zelle-Rieser, Claudia, Olivier, Angelika, Postert, Benno, Untergasser, Gerold, Kern, Johann, Brunner, Andrea, Gunsilius, Eberhard, Biedermann, Rainer, Hajek, Roman, Pour, Ludek, Willenbacher, Wolfgang, Greil, Richard, Jöhrer, Karin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346663/ https://www.ncbi.nlm.nih.gov/pubmed/27732933 http://dx.doi.org/10.18632/oncotarget.12522 |
Ejemplares similares
-
T cells in multiple myeloma display features of exhaustion and senescence at the tumor site
por: Zelle-Rieser, Claudia, et al.
Publicado: (2016) -
Expression and release of glucose-regulated protein-78 (GRP78) in multiple myeloma
por: Steiner, Normann, et al.
Publicado: (2017) -
High levels of FLT3-ligand in bone marrow and peripheral blood of patients with advanced multiple myeloma
por: Steiner, Normann, et al.
Publicado: (2017) -
Marine compounds inhibit growth of multiple myeloma in vitro and in vivo
por: Steiner, Normann, et al.
Publicado: (2015) -
Spliced XBP1 Levels Determine Sensitivity of Multiple Myeloma Cells to Proteasome Inhibitor Bortezomib Independent of the Unfolded Protein Response Mediator GRP78
por: Borjan, Bojana, et al.
Publicado: (2020)