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miR-125b regulates differentiation and metabolic reprogramming of T cell acute lymphoblastic leukemia by directly targeting A20

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematopoietic malignancy. Although it has been reported that overexpression of miR-125b leads to T-ALL development, the underlying mechanisms of miR-125b action are still unclear. The goal of this study is to delineate the role of miR-125b...

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Detalles Bibliográficos
Autores principales: Liu, Zixing, Smith, Kelly R., Khong, Hung T., Huang, Jingshan, Ahn, Eun-Young Erin, Zhou, Ming, Tan, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346668/
https://www.ncbi.nlm.nih.gov/pubmed/27637078
http://dx.doi.org/10.18632/oncotarget.12018