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Transcriptional upregulation of c-MET is associated with invasion and tumor budding in colorectal cancer

c-MET and its ligand HGF are frequently overexpressed in colorectal cancer (CRC) and increased c-MET levels are found in CRC liver metastases. This study investigated the role of the HGF/c-MET axis in regulating migration/invasion in CRC, using pre-clinical models and clinical samples. Pre-clinicall...

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Detalles Bibliográficos
Autores principales: Bradley, Conor A., Dunne, Philip D., Bingham, Victoria, McQuaid, Stephen, Khawaja, Hajrah, Craig, Stephanie, James, Jackie, Moore, Wendy L., McArt, Darragh G., Lawler, Mark, Dasgupta, Sonali, Johnston, Patrick G., Van Schaeybroeck, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346688/
https://www.ncbi.nlm.nih.gov/pubmed/27793046
http://dx.doi.org/10.18632/oncotarget.12933