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Attenuation of cancer-initiating cells stemness properties by abrogating S100A4 calcium binding ability in head and neck cancers

S100A4 is a calcium-binding protein capable of promoting epithelial-mesenchymal transition. Previously, we have demonstrated that S100A4 is required to sustain the head and neck cancer-initiating cells (HN-CICs) subpopulation. In this study, to further investigate the molecular mechanism, we establi...

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Detalles Bibliográficos
Autores principales: Cheng, Li-Hao, Hung, Kai-Feng, Huang, Tung-Fu, Hsieh, Hsin-Pei, Wang, Shu-Ying, Huang, Chih-Yang, Lo, Jeng-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346689/
https://www.ncbi.nlm.nih.gov/pubmed/27793047
http://dx.doi.org/10.18632/oncotarget.12935