Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells

Wnt signaling is implicated in bone formation and activated in breast cancer cells promoting primary and metastatic tumor growth. A compelling question is whether osteogenic miRNAs that increase Wnt activity for bone formation are aberrantly expressed in breast tumor cells to support metastatic bone...

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Detalles Bibliográficos
Autores principales: Taipaleenmäki, Hanna, Farina, Nicholas H., van Wijnen, Andre J., Stein, Janet L., Hesse, Eric, Stein, Gary S., Lian, Jane B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346696/
https://www.ncbi.nlm.nih.gov/pubmed/27738322
http://dx.doi.org/10.18632/oncotarget.12593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346696/
https://www.ncbi.nlm.nih.gov/pubmed/27738322
http://dx.doi.org/10.18632/oncotarget.12593

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