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Radiosensitizing effect of lapatinib in human epidermal growth factor receptor 2-positive breast cancer cells
Trastuzumab has been widely used for the treatment of human epidermal growth factor receptor 2 (HER2)-overexpressing breast cancer, however, it cannot easily cross the blood-brain barrier (BBB) and is known to increase the incidence of brain metastases. In contrast, lapatinib has a low molecular wei...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346700/ https://www.ncbi.nlm.nih.gov/pubmed/27738326 http://dx.doi.org/10.18632/oncotarget.12597 |