GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity

Abnormal activation of the epidermal growth factor receptor (EGFR) due to a deletion of exons 2-7 of EGFR (EGFRvIII) is a common alteration in glioblastoma (GBM). While this alteration can drive gliomagenesis, tumors harboring EGFRvIII are heterogeneous. To investigate the role for EGFRvIII activati...

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Detalles Bibliográficos
Autores principales: Lindberg, Olle R., McKinney, Andrew, Engler, Jane R., Koshkakaryan, Gayane, Gong, Henry, Robinson, Aaron E., Ewald, Andrew J., Huillard, Emmanuelle, James, C. David, Molinaro, Annette M., Shieh, Joseph T., Phillips, Joanna J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346701/
https://www.ncbi.nlm.nih.gov/pubmed/27738329
http://dx.doi.org/10.18632/oncotarget.12600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346701/
https://www.ncbi.nlm.nih.gov/pubmed/27738329
http://dx.doi.org/10.18632/oncotarget.12600

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