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Proteomic analysis reveals diverse proline hydroxylation-mediated oxygen-sensing cellular pathways in cancer cells

Proline hydroxylation is a critical cellular mechanism regulating oxygen-response pathways in tumor initiation and progression. Yet, its substrate diversity and functions remain largely unknown. Here, we report a system-wide analysis to characterize proline hydroxylation substrates in cancer cells u...

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Detalles Bibliográficos
Autores principales: Zhou, Tong, Erber, Luke, Liu, Bing, Gao, Yankun, Ruan, Hai-Bin, Chen, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346705/
https://www.ncbi.nlm.nih.gov/pubmed/27764789
http://dx.doi.org/10.18632/oncotarget.12632