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Genetic interactions between the hedgehog co-receptors Gas1 and Boc regulate cell proliferation during murine palatogenesis

Abnormal regulation of Sonic hedgehog (Shh) signaling has been described in a variety of human cancers and developmental anomalies, which highlights the essential role of this signaling molecule in cell cycle regulation and embryonic development. Gas1 and Boc are membrane co-receptors for Shh, which...

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Detalles Bibliográficos
Autores principales: Xavier, Guilherme M., Seppala, Maisa, Papageorgiou, Spyridon N., Fan, Chen-Ming, Cobourne, Martyn T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346710/
https://www.ncbi.nlm.nih.gov/pubmed/27811357
http://dx.doi.org/10.18632/oncotarget.13011