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Notch1—WISP-1 axis determines the regulatory role of mesenchymal stem cell-derived stromal fibroblasts in melanoma metastasis

Mesenchymal stem cells-derived fibroblasts (MSC-DF) constitute a significant portion of stromal fibroblasts in the tumor microenvironment (TME) and are key modulators of tumor progression. However, the molecular mechanisms that determine their tumor-regulatory function are poorly understood. Here, w...

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Detalles Bibliográficos
Autores principales: Shao, Hongwei, Cai, Long, Moller, Mecker, Issac, Biju, Zhang, Leiming, Owyong, Mark, Moscowitz, Anna Elizabeth, Vazquez-Padron, Roberto, Radtke, Freddy, Liu, Zhao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346712/
https://www.ncbi.nlm.nih.gov/pubmed/27813493
http://dx.doi.org/10.18632/oncotarget.13021