ON 01910.Na (rigosertib) inhibits PI3K/Akt pathway and activates oxidative stress signals in head and neck cancer cell lines

Squamous cell carcinoma of the head and neck (HNSCC) is characterized by high morbidity and mortality. Treatment failure, drug resistance and chemoradiation toxicity have necessitated the development of alternative treatment strategies. Styryl benzyl sulfones, a family of novel small molecule inhibi...

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Detalles Bibliográficos
Autores principales: Prasad, Anil, Khudaynazar, Nagina, Tantravahi, Ramana V., Gillum, Amanda M., Hoffman, Benjamin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346722/
https://www.ncbi.nlm.nih.gov/pubmed/27764820
http://dx.doi.org/10.18632/oncotarget.12692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346722/
https://www.ncbi.nlm.nih.gov/pubmed/27764820
http://dx.doi.org/10.18632/oncotarget.12692

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