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Identification of DNA-PKcs as a primary resistance factor of salinomycin in osteosarcoma cells

Malignant osteosarcoma (OS) is still a deadly disease for many affected patients. The search for the novel anti-OS agent is extremely urgent and important. Our previous study has proposed that salinomycin is a novel anti-OS agent. Here we characterized DNA-dependent protein kinase catalytic subunit...

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Detalles Bibliográficos
Autores principales: Zhen, Yun-fang, Li, Song-tao, Zhu, Yun-rong, Wang, Xiao-dong, Zhou, Xiao-zhong, Zhu, Lun-qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346724/
https://www.ncbi.nlm.nih.gov/pubmed/27765904
http://dx.doi.org/10.18632/oncotarget.12712