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Targeted NGS, array-CGH, and patient-derived tumor xenografts for precision medicine in advanced breast cancer: a single-center prospective study

BACKGROUND: Routine feasibility and clinical impact of genomics-based tumor profiling in advanced breast cancer (aBC) remains to be determined. We conducted a pilot study to evaluate whether precision medicine could be prospectively implemented for aBC patients in a single center and to examine whet...

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Detalles Bibliográficos
Autores principales: Gonçalves, Anthony, Bertucci, François, Guille, Arnaud, Garnier, Severine, Adelaide, José, Carbuccia, Nadine, Cabaud, Oliver, Finetti, Pascal, Brunelle, Serge, Piana, Gilles, Tomassin-Piana, Jeanne, Paciencia, Maria, Lambaudie, Eric, Popovici, Cornel, Sabatier, Renaud, Tarpin, Carole, Provansal, Magali, Extra, Jean-Marc, Eisinger, François, Sobol, Hagay, Viens, Patrice, Lopez, Marc, Ginestier, Christophe, Charafe-Jauffret, Emmanuelle, Chaffanet, Max, Birnbaum, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346725/
https://www.ncbi.nlm.nih.gov/pubmed/27765906
http://dx.doi.org/10.18632/oncotarget.12714