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MicroRNA-101 reverses temozolomide resistance by inhibition of GSK3β in glioblastoma

Glioblastoma multiforme (GBM) is a chemotherapy-resistant brain tumor with limited treatment options. Temozolomide (TMZ), an alkylating agent, is a front-line chemotherapeutic drug currently employed in GBM. Although it is currently the most promising chemotherapy for GBM, resistance to TMZ is also...

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Detalles Bibliográficos
Autores principales: Tian, Tian, Mingyi, Ma, Qiu, Xia, Qiu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346737/
https://www.ncbi.nlm.nih.gov/pubmed/27792996
http://dx.doi.org/10.18632/oncotarget.12861