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Breast cancer cells obtain an osteomimetic feature via epithelial-mesenchymal transition that have undergone BMP2/RUNX2 signaling pathway induction

Bone is one of the most common organs of breast cancer metastasis. Cancer cells that mimic osteoblasts by expressing bone matrix proteins and factors have a higher likelihood of metastasizing to bone. However, the molecular mechanisms of osteomimicry formation of cancer cells remain undefined. Herei...

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Detalles Bibliográficos
Autores principales: Tan, Cong-Cong, Li, Gui-Xi, Tan, Li-Duan, Du, Xin, Li, Xiao-Qing, He, Rui, Wang, Qing-Shan, Feng, Yu-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346745/
https://www.ncbi.nlm.nih.gov/pubmed/27806311
http://dx.doi.org/10.18632/oncotarget.12939