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Increased phosphorylation of eIF2α in chronic myeloid leukemia cells stimulates secretion of matrix modifying enzymes

Recent studies underscore the role of the microenvironment in therapy resistance of chronic myeloid leukemia (CML) cells and leukemia progression. We previously showed that sustained mild activation of endoplasmic reticulum (ER) stress in CML cells supports their survival and resistance to chemother...

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Detalles Bibliográficos
Autores principales: Podszywalow-Bartnicka, Paulina, Cmoch, Anna, Wolczyk, Magdalena, Bugajski, Lukasz, Tkaczyk, Marta, Dadlez, Michal, Nieborowska-Skorska, Margaret, Koromilas, Antonis E., Skorski, Tomasz, Piwocka, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346746/
https://www.ncbi.nlm.nih.gov/pubmed/27802179
http://dx.doi.org/10.18632/oncotarget.12941