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Association of Bax Expression and Bcl2/Bax Ratio with Clinical and Molecular Prognostic Markers in Chronic Lymphocytic Leukemia

BACKGROUND: In chronic lymphocytic leukemia (CLL), in vivo apoptotic resistance of malignant B lymphocytes results, in part, from the intrinsic defects of their apoptotic machinery. These include genetic alterations and aberrant expression of many apoptosis regulators, among which the Bcl2 family me...

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Detalles Bibliográficos
Autores principales: Vucicevic, Ksenija, Jakovljevic, Vladimir, Colovic, Natasa, Tosic, Natasa, Kostic, Tatjana, Glumac, Irena, Pavlovic, Sonja, Karan-Djurasevic, Teodora, Colovic, Milica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Medical Biochemists of Serbia 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346792/
https://www.ncbi.nlm.nih.gov/pubmed/28356875
http://dx.doi.org/10.1515/jomb-2015-0017