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NLRP3 and CARD8 Polymorphisms Influence Higher Disease Activity in Rheumatoid Arthritis

BACKGROUND: The activation of NLRP3-inflammasome may contribute to inflammatory processes in rheumatoid arthritis (RA). Functional polymorphisms in the genes coding for its components NLRP3 and CARD8 were associated with a proinflammatory phenotype. Our aim was to investigate the influence of these...

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Detalles Bibliográficos
Autores principales: Jenko, Barbara, Praprotnik, Sonja, Tomšic, Matija, Dolžan, Vita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Medical Biochemists of Serbia 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346810/
https://www.ncbi.nlm.nih.gov/pubmed/28356883
http://dx.doi.org/10.1515/jomb-2016-0008