Cargando…

NLRP3 and CARD8 Polymorphisms Influence Higher Disease Activity in Rheumatoid Arthritis

BACKGROUND: The activation of NLRP3-inflammasome may contribute to inflammatory processes in rheumatoid arthritis (RA). Functional polymorphisms in the genes coding for its components NLRP3 and CARD8 were associated with a proinflammatory phenotype. Our aim was to investigate the influence of these...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jenko, Barbara, Praprotnik, Sonja, Tomšic, Matija, Dolžan, Vita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society of Medical Biochemists of Serbia 2016
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346810/ https://www.ncbi.nlm.nih.gov/pubmed/28356883 http://dx.doi.org/10.1515/jomb-2016-0008

Ejemplares similares

Clinical Pharmacogenetic Models of Treatment Response to Methotrexate Monotherapy in Slovenian and Serbian Rheumatoid Arthritis Patients: Differences in Patient's Management May Preclude Generalization of the Models
por: Jenko, Barbara, et al.
Publicado: (2018)

NLRP3 and CARD8 polymorphisms influence risk for asbestos-related diseases
por: Franko, Alenka, et al.
Publicado: (2020)

Genetic Polymorphisms Modifying Oxidative Stress Are Associated with Disease Activity in Rheumatoid Arthritis Patients
por: Bohanec Grabar, Petra, et al.
Publicado: (2009)

Associations of NLRP3 and CARD8 Gene Polymorphisms with Alcohol Dependence and Commonly Related Psychiatric Disorders: a Preliminary Study
por: Ilješ, Anja Plemenitaš, et al.
Publicado: (2021)

CARD8 and IL1B Polymorphisms Influence MRI Brain Patterns in Newborns with Hypoxic-Ischemic Encephalopathy Treated with Hypothermia
por: Esih, Katarina, et al.
Publicado: (2021)

Tuberculosis among patients treated with TNF inhibitors for rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis in Slovenia: a cohort study
por: Rotar, Ziga, et al.
Publicado: (2020)

The NLRP1 and CARD8 inflammasomes
por: Taabazuing, Cornelius Y., et al.
Publicado: (2020)

NLRP3 gene polymorphisms and expression in rheumatoid arthritis
por: Cheng, Lin, et al.
Publicado: (2021)

NLRP3 Inflammasome Polymorphism and Macrovascular Complications in Type 2 Diabetes Patients
por: Klen, Jasna, et al.
Publicado: (2015)

Access to biologic treatment for rheumatoid arthritis in Central and Eastern European (CEE) countries
por: Orlewska, Ewa, et al.
Publicado: (2011)

Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells
por: Kuret, Tadeja, et al.
Publicado: (2018)

Clinical-Pharmacogenetic Predictive Models for Time to Occurrence of Levodopa Related Motor Complications in Parkinson’s Disease
por: Redenšek, Sara, et al.
Publicado: (2019)

Clinical and Clinical-Pharmacogenetic Models for Prediction of the Most Common Psychiatric Complications Due to Dopaminergic Treatment in Parkinson’s Disease
por: Redenšek, Sara, et al.
Publicado: (2020)

Genetic Polymorphisms of NLRP3 (rs4612666) and CARD8 (rs2043211) in Periodontitis and Cardiovascular Diseases
por: Mahendra, Jaideep, et al.
Publicado: (2021)

The NLRP1 and CARD8 inflammasomes detect reductive stress
por: Wang, Qinghui, et al.
Publicado: (2023)

NLRP3 Gene Polymorphisms in Rheumatoid Arthritis and Primary Sjogren’s Syndrome Patients
por: Li, Ruei-Nian, et al.
Publicado: (2023)

Polymorphisms in CARD8 and NLRP3 are associated with extrapulmonary TB and poor clinical outcome in active TB in Ethiopia
por: Abate, Ebba, et al.
Publicado: (2019)

Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome
por: Xu, Zhihao, et al.
Publicado: (2021)

Role of Genetic Alterations in the NLRP3 and CARD8 Genes in Health and Disease
por: Paramel, G. V., et al.
Publicado: (2015)

Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes
por: Robert Hollingsworth, L., et al.
Publicado: (2021)

Replication study of polymorphisms associated with response to methotrexate in patients with rheumatoid arthritis
por: López-Rodríguez, Rosario, et al.
Publicado: (2018)

Role of NLRP3 Inflammasome in Rheumatoid Arthritis
por: Yin, Hui, et al.
Publicado: (2022)

Homologous Recombination Repair Polymorphisms and the Risk for Osteosarcoma
por: Goričar, Katja, et al.
Publicado: (2015)

Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8
por: Gong, Qin, et al.
Publicado: (2021)

The CARD8 T60 variant associates with NLRP1 and negatively regulates its activation
por: Xu, Zhihao, et al.
Publicado: (2022)

Corrigendum: Role of NLRP3 inflammasome in rheumatoid arthritis
por: Yin, Hui, et al.
Publicado: (2023)

Genetic polymorphisms in homologous recombination repair genes in healthy Slovenian population and their influence on DNA damage
por: Goricar, Katja, et al.
Publicado: (2012)

The influence of folate pathway polymorphisms on high-dose methotrexate-related toxicity and survival in children with non-Hodgkin malignant lymphoma
por: Erculj, Nina, et al.
Publicado: (2014)

Dual Role of PTPN22 but Not NLRP3 Inflammasome Polymorphisms in Type 1 Diabetes and Celiac Disease in Children
por: Smigoc Schweiger, Darja, et al.
Publicado: (2019)

Detection of metabolic syndrome burden in healthy young adults may enable timely introduction of disease prevention
por: Šoštarič, Anja, et al.
Publicado: (2019)

Genetic variability in sodium-glucose cotransporter 2 influences glycemic control and risk for diabetic retinopathy in type 2 diabetes patients
por: Klen, Jasna, et al.
Publicado: (2020)

CARD8 is a negative regulator for NLRP3 inflammasome, but mutant NLRP3 in cryopyrin-associated periodic syndromes escapes the restriction
por: Ito, Sayaka, et al.
Publicado: (2014)

Functional polymorphisms in antioxidant genes in Hurthle cell thyroid neoplasm - an association of GPX1 polymorphism and recurrent Hurthle cell thyroid carcinoma
por: Krhin, Blaz, et al.
Publicado: (2016)

CARD8 and NLRP1 Undergo Autoproteolytic Processing through a ZU5-Like Domain
por: D'Osualdo, Andrea, et al.
Publicado: (2011)

VEGF-C Gene Polymorphisms Increase Susceptibility to Rheumatoid Arthritis
por: Dai, Chengqian, et al.
Publicado: (2019)

Influence of Promoter Polymorphisms of the TNF-α (-308G/A) and IL-6 (-174G/C) Genes on Therapeutic Response to Etanercept in Rheumatoid Arthritis
por: Jančić, Ivan, et al.
Publicado: (2015)

C10X polymorphism in the CARD8 gene is associated with bacteraemia
por: Asfaw Idosa, Berhane, et al.
Publicado: (2014)

Tofacitinib restores the balance of γδTreg/γδT17 cells in rheumatoid arthritis by inhibiting the NLRP3 inflammasome
por: Yang, Xinyu, et al.
Publicado: (2021)

Lack of significant association between selected STAT3 polymorphisms and rheumatoid arthritis in the Polish population
por: Stypińska, Barbara, et al.
Publicado: (2018)

Antioxidant defence-related genetic variants are not associated with higher risk of secondary thyroid cancer after treatment of malignancy in childhood or adolescence
por: Vodusek, Ana Lina, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ie9fr751qv24iq7rmuatklkku4