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Scaling clearance in paediatric pharmacokinetics: All models are wrong, which are useful?

LINKED ARTICLES: This article is commented on in the editorial by Holford NHG and Anderson BJ. Why standards are useful for predicting doses. Br J Clin Pharmacol 2017; 83: 685–7. doi: 10.1111/bcp.13230 AIM: When different models for weight and age are used in paediatric pharmacokinetic studies it is...

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Detalles Bibliográficos
Autores principales: Germovsek, Eva, Barker, Charlotte I. S., Sharland, Mike, Standing, Joseph F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346879/
https://www.ncbi.nlm.nih.gov/pubmed/27767204
http://dx.doi.org/10.1111/bcp.13160