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Antimalarial Properties of Simplified Kalihinol Analogues

[Image: see text] Several kalihinol natural products, members of the broader isocyanoterpene family of antimalarial agents, are potent inhibitors of Plasmodium falciparum, the agent of the most severe form of human malaria. Our previous total synthesis of kalihinol B provided a blueprint to generate...

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Detalles Bibliográficos
Autores principales: Daub, Mary Elisabeth, Prudhomme, Jacques, Ben Mamoun, Choukri, Le Roch, Karine G., Vanderwal, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346982/
https://www.ncbi.nlm.nih.gov/pubmed/28337330
http://dx.doi.org/10.1021/acsmedchemlett.7b00013