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DNA-conjugated gold nanoparticles based colorimetric assay to assess helicase activity: a novel route to screen potential helicase inhibitors

Helicase are essential enzymes which are widespread in all life-forms. Due to their central role in nucleic acid metabolism, they are emerging as important targets for anti-viral, antibacterial and anti-cancer drugs. The development of easy, cheap, fast and robust biochemical assays to measure helic...

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Detalles Bibliográficos
Autores principales: Deka, Jashmini, Mojumdar, Aditya, Parisse, Pietro, Onesti, Silvia, Casalis, Loredana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347027/
https://www.ncbi.nlm.nih.gov/pubmed/28287182
http://dx.doi.org/10.1038/srep44358