Crystal structure of 6,7-dimeth­oxy-1-(4-nitro­phen­yl)quinolin-4(1H)-one: a mol­ecular scaffold for potential tubulin polymerization inhibitors

The protein tubulin is central for maintaining normal cellular processes, and mol­ecules inter­fering with the tubulin dynamics have potential in the treatment of cancerous diseases. The title compound, C(17)H(14)N(2)O(5), was prepared as a lead compound in a project dedicated to the development of...

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Detalles Bibliográficos
Autores principales: Lien, Vegard Torp, Olberg, Dag Erlend, Klaveness, Jo, Görbitz, Carl Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2017
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347072/
https://www.ncbi.nlm.nih.gov/pubmed/28316827
http://dx.doi.org/10.1107/S2056989017002948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347072/
https://www.ncbi.nlm.nih.gov/pubmed/28316827
http://dx.doi.org/10.1107/S2056989017002948

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