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Single Molecule Investigation of Kinesin-1 Motility Using Engineered Microtubule Defects

The structure of the microtubule is tightly regulated in cells via a number of microtubule associated proteins and enzymes. Microtubules accumulate structural defects during polymerization, and defect size can further increase under mechanical stresses. Intriguingly, microtubule defects have been sh...

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Detalles Bibliográficos
Autores principales: Gramlich, Michael W., Conway, Leslie, Liang, Winnie H., Labastide, Joelle A., King, Stephen J., Xu, Jing, Ross, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347089/
https://www.ncbi.nlm.nih.gov/pubmed/28287156
http://dx.doi.org/10.1038/srep44290