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Single Molecule Investigation of Kinesin-1 Motility Using Engineered Microtubule Defects
The structure of the microtubule is tightly regulated in cells via a number of microtubule associated proteins and enzymes. Microtubules accumulate structural defects during polymerization, and defect size can further increase under mechanical stresses. Intriguingly, microtubule defects have been sh...
Autores principales: | Gramlich, Michael W., Conway, Leslie, Liang, Winnie H., Labastide, Joelle A., King, Stephen J., Xu, Jing, Ross, Jennifer L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347089/ https://www.ncbi.nlm.nih.gov/pubmed/28287156 http://dx.doi.org/10.1038/srep44290 |
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