Cargando…

CD40-signalling abrogates induction of RORγt(+) Treg cells by intestinal CD103(+) DCs and causes fatal colitis

Immune homeostasis in intestinal tissues depends on the generation of regulatory T (Treg) cells. CD103(+) dendritic cells (DCs) acquire microbiota-derived material from the gut lumen for transport to draining lymph nodes and generation of receptor-related orphan γt(+) (RORγt(+)) Helios(−)-induced Tr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barthels, Christian, Ogrinc, Ana, Steyer, Verena, Meier, Stefanie, Simon, Ferdinand, Wimmer, Maria, Blutke, Andreas, Straub, Tobias, Zimber-Strobl, Ursula, Lutgens, Esther, Marconi, Peggy, Ohnmacht, Caspar, Garzetti, Debora, Stecher, Bärbel, Brocker, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347138/ https://www.ncbi.nlm.nih.gov/pubmed/28276457 http://dx.doi.org/10.1038/ncomms14715

Ejemplares similares

Erratum: CD40-signalling abrogates induction of RORγt(+) Treg cells by intestinal CD103(+) DCs and causes fatal colitis
por: Barthels, Christian, et al.
Publicado: (2017)

Strain specific maturation of Dendritic cells and production of IL-1β controls CD40-driven colitis
por: Ogrinc Wagner, Ana, et al.
Publicado: (2019)

The origin and development of nonlymphoid tissue CD103(+) DCs
por: Ginhoux, Florent, et al.
Publicado: (2009)

The Closely Related CD103(+) Dendritic Cells (DCs) and Lymphoid-Resident CD8(+) DCs Differ in Their Inflammatory Functions
por: Jiao, Zhijun, et al.
Publicado: (2014)

Goblet cells deliver luminal antigen to CD103(+) DCs in the small intestine
por: McDole, Jeremiah R., et al.
Publicado: (2012)

Mesenchymal stem cells alleviate rat diabetic nephropathy by suppressing CD103(+) DCs‐mediated CD8(+) T cell responses
por: Zhang, Fuping, et al.
Publicado: (2020)

Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity
por: Ohnmacht, Caspar, et al.
Publicado: (2009)

Complete Genome Sequencing of the Mouse Intestinal Isolate Escherichia coli Mt1B1
por: Garzetti, Debora, et al.
Publicado: (2018)

Co‐immunization with L‐Myc enhances CD8(+) or CD103(+) DCs mediated tumor‐specific multi‐functional CD8(+) T cell responses
por: Chai, Dafei, et al.
Publicado: (2021)

Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103(+)CD11b(+) DCs in the intestinal lamina propria
por: Scott, Charlotte L, et al.
Publicado: (2014)

CD103 spurs on suppressors
por: Van Epps, Heather L.
Publicado: (2005)

Loss of CD103+ DCs and Mucosal IL-17+ and IL-22+ Lymphocytes is Associated with Mucosal Damage in SIV Infection
por: Klatt, Nichole R., et al.
Publicado: (2012)

Microbiota-activated CD103(+) DCs stemming from microbiota adaptation specifically drive γδT17 proliferation and activation
por: Fleming, Chris, et al.
Publicado: (2017)

Silencing RORγt in Human CD4(+) T cells with CD30 aptamer-RORγt shRNA Chimera
por: Shi, Xiaofei, et al.
Publicado: (2019)

RelB contributes to the survival, migration and lymphomagenesis of B cells with constitutively active CD40 signaling
por: Kuhn, Laura B., et al.
Publicado: (2022)

CD103 in the development of experimental asthma
por: Blanchet, Marie-Renee, et al.
Publicado: (2010)

Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORγt and LTi cells
por: Lochner, Matthias, et al.
Publicado: (2011)

Intestinal CD103(+)CD4(+) and CD103(+)CD8(+) T-Cell Subsets in the Gut of Inflammatory Bowel Disease Patients at Diagnosis and During Follow-up
por: Roosenboom, Britt, et al.
Publicado: (2019)

Infiltration and Significance of CD103+CD8+ T Cells in Gastrointestinal Adenocarcinoma
por: Cai, Weisu, et al.
Publicado: (2022)

Accumulation of CD103(+) CD8(+) T cells in a cutaneous melanoma micrometastasis
por: Hochheiser, Katharina, et al.
Publicado: (2019)

TGF-β: Many Paths to CD103(+) CD8 T Cell Residency
por: Qiu, Zhijuan, et al.
Publicado: (2021)

Pivotal role of CD103 in the development of psoriasiform dermatitis
por: Fukui, Takehito, et al.
Publicado: (2020)

CD103 Expression Is Required for Destruction of Pancreatic Islet Allografts by CD8(+) T Cells
por: Feng, Ye, et al.
Publicado: (2002)

Human dendritic cells (DCs) are derived from distinct circulating precursors that are precommitted to become CD1c(+) or CD141(+) DCs
por: Breton, Gaëlle, et al.
Publicado: (2016)

Influenza-Induced CD103(+) T Resident Memory Cells Exhibit Enhanced Functional Avidity over CD103(−) Memory T Cells in the Mediastinal Lymph Node
por: Crooks, Sequoia D., et al.
Publicado: (2022)

A functionally specialized population of mucosal CD103(+) DCs induces Foxp3(+) regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism
por: Coombes, Janine L., et al.
Publicado: (2007)

Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade
por: Banchereau, Romain, et al.
Publicado: (2021)

Assessing the Role of CD103 in Immunity to an Intestinal Helminth Parasite
por: Mullaly, Sarah C., et al.
Publicado: (2011)

Eribulin mesylate exerts antitumor effects via CD103
por: Oya, Kazumasa, et al.
Publicado: (2023)

CD103(+) Cells and Chemokine Receptor Expression in Breast Cancer
por: Seo, Eun-Hye, et al.
Publicado: (2023)

CD103−CD11b+ dendritic cells regulate the sensitivity of CD4 T cell responses to bacterial flagellin
por: Atif, Shaikh M., et al.
Publicado: (2013)

Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors
por: Duhen, Thomas, et al.
Publicado: (2018)

Transcriptional Activity and Stability of CD39+CD103+CD8+ T Cells in Human High-Grade Endometrial Cancer
por: Workel, Hagma H., et al.
Publicado: (2020)

CD147: an integral and potential molecule to abrogate hallmarks of cancer
por: Nyalali, Alphonce M. K., et al.
Publicado: (2023)

Development of [(89)Zr]Zr-hCD103.Fab01A and [(68)Ga]Ga-hCD103.Fab01A for PET imaging to noninvasively assess cancer reactive T cell infiltration: Fab-based CD103 immunoPET
por: Fan, Xiaoyu, et al.
Publicado: (2023)

Cytokines and TLR agonists influence the expression of retention integrins CD49a, CD49b and CD103 by T cells
por: Melssen, Marit M, et al.
Publicado: (2015)

Aging impacts CD103(+) CD8(+) T cell presence and induction by dendritic cells in the genital tract
por: Rodriguez‐Garcia, Marta, et al.
Publicado: (2018)

CD103-CD23+ classical hair cell leukemia: A case report and review of the literature
por: Zhao, Hong-li, et al.
Publicado: (2021)

RORα Regulates Cholesterol Metabolism of CD8(+) T Cells for Anticancer Immunity
por: Lee, In Kyu, et al.
Publicado: (2020)

Essential role for CD103 in the T cell–mediated regulation of experimental colitis
por: Annacker, Oliver, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_oqv0jj3edtie75solu4o21smko