AKT1 and AKT2 isoforms play distinct roles during breast cancer progression through the regulation of specific downstream proteins

The purpose of this study was to elucidate the mechanisms associated with the specific effects of AKT1 and AKT2 isoforms in breast cancer progression. We modulated the abundance of specific AKT isoforms in IBH-6 and T47D human breast cancer cell lines and showed that AKT1 promoted cell proliferation...

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Detalles Bibliográficos
Autores principales: Riggio, Marina, Perrone, María C., Polo, María L., Rodriguez, María J., May, María, Abba, Martín, Lanari, Claudia, Novaro, Virginia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347151/
https://www.ncbi.nlm.nih.gov/pubmed/28287129
http://dx.doi.org/10.1038/srep44244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347151/
https://www.ncbi.nlm.nih.gov/pubmed/28287129
http://dx.doi.org/10.1038/srep44244

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