Unexpected selections of Plasmodium falciparum polymorphisms in previously treatment-naïve areas after monthly presumptive administration of three different anti-malarial drugs in Liberia 1976–78

BACKGROUND: To assess the effect on malaria prevalence, village specific monthly administrations of pyrimethamine, chlorproguanil, chloroquine or placebo were given to children in four previously treatment-naïve Liberian villages, 1976–78. Plasmodium falciparum in vivo resistance developed to pyrime...

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Detalles Bibliográficos
Autores principales: Jovel, Irina T., Björkman, Anders, Roper, Cally, Mårtensson, Andreas, Ursing, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347173/
https://www.ncbi.nlm.nih.gov/pubmed/28288632
http://dx.doi.org/10.1186/s12936-017-1747-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347173/
https://www.ncbi.nlm.nih.gov/pubmed/28288632
http://dx.doi.org/10.1186/s12936-017-1747-6

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