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Unexpected selections of Plasmodium falciparum polymorphisms in previously treatment-naïve areas after monthly presumptive administration of three different anti-malarial drugs in Liberia 1976–78

BACKGROUND: To assess the effect on malaria prevalence, village specific monthly administrations of pyrimethamine, chlorproguanil, chloroquine or placebo were given to children in four previously treatment-naïve Liberian villages, 1976–78. Plasmodium falciparum in vivo resistance developed to pyrime...

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Detalles Bibliográficos
Autores principales:	Jovel, Irina T., Björkman, Anders, Roper, Cally, Mårtensson, Andreas, Ursing, Johan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347173/ https://www.ncbi.nlm.nih.gov/pubmed/28288632 http://dx.doi.org/10.1186/s12936-017-1747-6

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