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Bicodon bias can determine the role of synonymous SNPs in human diseases
BACKGROUND: For a long time synonymous single nucleotide polymorphisms were considered as silent mutations. However, nowadays it is well known that they can affect protein conformation and function, leading to altered disease susceptibilities, differential prognosis and/or drug responses, among othe...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347174/ https://www.ncbi.nlm.nih.gov/pubmed/28288557 http://dx.doi.org/10.1186/s12864-017-3609-6 |