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New Mouse Model for Chronic Infections by Gram-Negative Bacteria Enabling the Study of Anti-Infective Efficacy and Host-Microbe Interactions

Only a few, relatively cumbersome animal models enable long-term Gram-negative bacterial infections that mimic human situations, where untreated infections can last for weeks. Here, we describe a simple murine cutaneous abscess model that enables chronic or progressive infections, depending on the s...

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Detalles Bibliográficos
Autores principales: Pletzer, Daniel, Mansour, Sarah C., Wuerth, Kelli, Rahanjam, Negin, Hancock, Robert E. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347345/
https://www.ncbi.nlm.nih.gov/pubmed/28246361
http://dx.doi.org/10.1128/mBio.00140-17