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Multivariate simulation framework reveals performance of multi-trait GWAS methods

Burgeoning availability of genome-wide association study (GWAS) results and national biobank data has led to growing interest in performing multi-trait genetic analyses. Numerous multi-trait GWAS methods that exploit either summary statistics or individual-level data have been developed, but their r...

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Detalles Bibliográficos
Autores principales: Porter, Heather F., O’Reilly, Paul F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347376/
https://www.ncbi.nlm.nih.gov/pubmed/28287610
http://dx.doi.org/10.1038/srep38837