Restoring the impaired cardiac calcium homeostasis and cardiac function in iron overload rats by the combined deferiprone and N-acetyl cysteine

Intracellular calcium [Ca(2+)](i) dysregulation plays an important role in the pathophysiology of iron overload cardiomyopathy. Although either iron chelators or antioxidants provide cardioprotection, a comparison of the efficacy of deferoxamine (DFO), deferiprone (DFP), deferasirox (DFX), N-acetyl...

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Detalles Bibliográficos
Autores principales: Wongjaikam, Suwakon, Kumfu, Sirinart, Khamseekaew, Juthamas, Chattipakorn, Siriporn C., Chattipakorn, Nipon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347387/
https://www.ncbi.nlm.nih.gov/pubmed/28287621
http://dx.doi.org/10.1038/srep44460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347387/
https://www.ncbi.nlm.nih.gov/pubmed/28287621
http://dx.doi.org/10.1038/srep44460

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