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Restoring the impaired cardiac calcium homeostasis and cardiac function in iron overload rats by the combined deferiprone and N-acetyl cysteine
Intracellular calcium [Ca(2+)](i) dysregulation plays an important role in the pathophysiology of iron overload cardiomyopathy. Although either iron chelators or antioxidants provide cardioprotection, a comparison of the efficacy of deferoxamine (DFO), deferiprone (DFP), deferasirox (DFX), N-acetyl...
Autores principales: | Wongjaikam, Suwakon, Kumfu, Sirinart, Khamseekaew, Juthamas, Chattipakorn, Siriporn C., Chattipakorn, Nipon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347387/ https://www.ncbi.nlm.nih.gov/pubmed/28287621 http://dx.doi.org/10.1038/srep44460 |
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