A codon-shuffling method to prevent reversion during production of replication-defective herpesvirus stocks: Implications for herpesvirus vaccines

Herpesviruses establish life-long chronic infections that place infected hosts at risk for severe disease. Herpesvirus genomes readily undergo homologous recombination (HR) during productive replication, often leading to wild-type (WT) reversion during complementation of replication-defective and at...

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Detalles Bibliográficos
Autores principales: Li, Gang, Ward, Charles, Yeasmin, Rukhsana, Skiena, Steven, Krug, Laurie T., Forrest, J. Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347388/
https://www.ncbi.nlm.nih.gov/pubmed/28287622
http://dx.doi.org/10.1038/srep44404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347388/
https://www.ncbi.nlm.nih.gov/pubmed/28287622
http://dx.doi.org/10.1038/srep44404

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