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Mathematical models of tissue stem and transit target cell divisions and the risk of radiation- or smoking-associated cancer
There is compelling biological data to suggest that cancer arises from a series of mutations in single target cells, resulting in defects in cell renewal and differentiation processes which lead to malignancy. Because much mutagenic damage is expressed following cell division, more-rapidly renewing...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347390/ https://www.ncbi.nlm.nih.gov/pubmed/28196079 http://dx.doi.org/10.1371/journal.pcbi.1005391 |