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The role for infarct volume as a surrogate measure of functional outcome following ischemic stroke

The failed translation of proposed therapeutic agents for ischemic stroke from preclinical to clinical studies has led to increased scrutiny of preclinical studies, namely the model and outcome measures utilized. Preclinical studies routinely use infarct volume as an experimental endpoint or measure...

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Detalles Bibliográficos
Autores principales: Turner, Ryan C, DiPasquale, Kenneth, Logsdon, Aric F, Tan, Zhenjun, Naser, Zachary J, Huber, Jason D, Rosen, Charles L, Lucke-Wold, Brandon P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347398/
https://www.ncbi.nlm.nih.gov/pubmed/28299202