Cargando…
Enantioselective amine α-functionalization via palladium catalyzed C–H arylation of thioamides
Saturated aza-heterocycles are highly privileged building blocks that are commonly encountered in bioactive compounds and approved therapeutic agents. These N-heterocycles are also incorporated as chiral auxiliaries and ligands in asymmetric synthesis. As such, development of methods to functionaliz...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347480/ https://www.ncbi.nlm.nih.gov/pubmed/28282045 http://dx.doi.org/10.1038/nchem.2619 |