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Pattern of RECK CpG methylation as a potential marker for predicting breast cancer prognosis and drug-sensitivity
The membrane-anchored glycoprotein RECK negatively regulates multiple metalloproteinases and is frequently downregulated in tumors. Forced RECK expression in cancer cells results in suppression of tumor angiogenesis, invasion, and metastasis in xenograft models. A previous methylome study on breast...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347682/ https://www.ncbi.nlm.nih.gov/pubmed/27058625 http://dx.doi.org/10.18632/oncotarget.8620 |