Cranial irradiation induces transient microglia accumulation, followed by long-lasting inflammation and loss of microglia

The relative contribution of resident microglia and peripheral monocyte-derived macrophages in neuroinflammation after cranial irradiation is not known. A single dose of 8 Gy was administered to postnatal day 10 (juvenile) or 90 (adult) CX3CR1(GFP/+) CCR2(RFP/+) mouse brains. Microglia accumulated i...

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Detalles Bibliográficos
Autores principales: Han, Wei, Umekawa, Takashi, Zhou, Kai, Zhang, Xing-Mei, Ohshima, Makiko, Dominguez, Cecilia A., Harris, Robert A., Zhu, Changlian, Blomgren, Klas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347693/
https://www.ncbi.nlm.nih.gov/pubmed/27793054
http://dx.doi.org/10.18632/oncotarget.12929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347693/
https://www.ncbi.nlm.nih.gov/pubmed/27793054
http://dx.doi.org/10.18632/oncotarget.12929

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