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Multiparameter comparative analysis reveals differential impacts of various cytokines on CART cell phenotype and function ex vivo and in vivo

Exogenous cytokines are widely applied to enhance the anti-tumor ability of immune cells. However, systematic comparative studies of their effects on chimeric antigen receptor (CAR)-engineered T (CART) cells are lacking. In this study, CART cells targeting folate receptor-alpha were generated and ex...

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Detalles Bibliográficos
Autores principales: Xu, Xiao-Jun, Song, De-Gang, Poussin, Mathilde, Ye, Qunrui, Sharma, Prannda, Rodríguez-García, Alba, Tang, Yong-Min, Powell, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347696/
https://www.ncbi.nlm.nih.gov/pubmed/27409425
http://dx.doi.org/10.18632/oncotarget.10510