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Multiparameter comparative analysis reveals differential impacts of various cytokines on CART cell phenotype and function ex vivo and in vivo
Exogenous cytokines are widely applied to enhance the anti-tumor ability of immune cells. However, systematic comparative studies of their effects on chimeric antigen receptor (CAR)-engineered T (CART) cells are lacking. In this study, CART cells targeting folate receptor-alpha were generated and ex...
Autores principales: | Xu, Xiao-Jun, Song, De-Gang, Poussin, Mathilde, Ye, Qunrui, Sharma, Prannda, Rodríguez-García, Alba, Tang, Yong-Min, Powell, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347696/ https://www.ncbi.nlm.nih.gov/pubmed/27409425 http://dx.doi.org/10.18632/oncotarget.10510 |
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