Epigenetic silencing of tumor suppressor long non-coding RNA BM742401 in chronic lymphocytic leukemia

BM742401 is a tumor suppressor lncRNA downregulated in gastric cancer. As the promoter region and the entire transcript are embedded in a CpG island, we postulated that BM742401 is a tumor suppressor lncRNA inactivated by DNA methylation in chronic lymphocytic leukemia (CLL). The promoter of BM74240...

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Detalles Bibliográficos
Autores principales: Wang, Lu Qian, Wong, Kwan Yeung, Li, Zhen Hai, Chim, Chor Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347700/
https://www.ncbi.nlm.nih.gov/pubmed/27689399
http://dx.doi.org/10.18632/oncotarget.12252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347700/
https://www.ncbi.nlm.nih.gov/pubmed/27689399
http://dx.doi.org/10.18632/oncotarget.12252

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