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Epigenetic silencing of tumor suppressor long non-coding RNA BM742401 in chronic lymphocytic leukemia
BM742401 is a tumor suppressor lncRNA downregulated in gastric cancer. As the promoter region and the entire transcript are embedded in a CpG island, we postulated that BM742401 is a tumor suppressor lncRNA inactivated by DNA methylation in chronic lymphocytic leukemia (CLL). The promoter of BM74240...
Autores principales: | Wang, Lu Qian, Wong, Kwan Yeung, Li, Zhen Hai, Chim, Chor Sang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347700/ https://www.ncbi.nlm.nih.gov/pubmed/27689399 http://dx.doi.org/10.18632/oncotarget.12252 |
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