Phosphatidyl inositol-3 kinase (PIK3CA) E545K mutation confers cisplatin resistance and a migratory phenotype in cervical cancer cells

The phosphatidylinositol-3 kinase (PI3K)/Akt/mTOR signaling pathway is activated in many human cancers. Previously, we reported that patients with early stage cervical cancer whose tumours harbour PIK3CA exon 9 or 20 mutations have worse overall survival in response to treatment with radiation and c...

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Detalles Bibliográficos
Autores principales: Arjumand, Wani, Merry, Cole D., Wang, Chen, Saba, Elias, McIntyre, John B., Fang, Shujuan, Kornaga, Elizabeth, Ghatage, Prafull, Doll, Corinne M., Lees, Susan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347702/
https://www.ncbi.nlm.nih.gov/pubmed/27489350
http://dx.doi.org/10.18632/oncotarget.10955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347702/
https://www.ncbi.nlm.nih.gov/pubmed/27489350
http://dx.doi.org/10.18632/oncotarget.10955

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