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IGF-1 contributes to the expansion of melanoma-initiating cells through an epithelial-mesenchymal transition process

Melanoma is a particularly virulent human cancer, due to its resistance to conventional treatments and high frequency of metastasis. Melanomas contain a fraction of cells, the melanoma-initiating cells (MICs), responsible for tumor propagation and relapse. Identification of the molecular pathways su...

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Detalles Bibliográficos
Autores principales: Le Coz, Vincent, Zhu, Chaobin, Devocelle, Aurore, Vazquez, Aimé, Boucheix, Claude, Azzi, Sandy, Gallerne, Cindy, Eid, Pierre, Lecourt, Séverine, Giron-Michel, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347710/
https://www.ncbi.nlm.nih.gov/pubmed/27764776
http://dx.doi.org/10.18632/oncotarget.12733