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IGF-1 contributes to the expansion of melanoma-initiating cells through an epithelial-mesenchymal transition process
Melanoma is a particularly virulent human cancer, due to its resistance to conventional treatments and high frequency of metastasis. Melanomas contain a fraction of cells, the melanoma-initiating cells (MICs), responsible for tumor propagation and relapse. Identification of the molecular pathways su...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347710/ https://www.ncbi.nlm.nih.gov/pubmed/27764776 http://dx.doi.org/10.18632/oncotarget.12733 |